San Antonio Real Estate Search

San Antonio Commercial Properties for Sale

Our website features the best real estate search for commercial properties available in San Antonio and surrounding areas. It is the only site you will ever need! It is easy-to-use and updated by the official REALTOR®’s database every 15 minutes. 

You can save searches, and get daily email alerts of new listings, price changes, sold data, and market reports. Our Interactive Map Search allows you to view properties on a map or refine your search by drawing the boundaries around the area you desire.

Curious about what’s happening in the San Antonio real estate market? Sign up for a  San Antonio Real Estate Market Report to see what’s active, under contract, and sold!

Considering selling or refinancing your home? Get an INSTANT property valuation now!

Newest San Antonio Commercial Properties for Sale

5902 Computer Dr, San Antonio
$3,800,000
2003453 MLS
Medical Office Investment Opportunity | Priced Below Appraised Value for Immediate Sale Position your portfolio with this exceptional value-add medical office investment in one of San Antonio's most established healthcare and business corridors. Strategically located near the intersection of Interstate 10 and Wurzbach Road, this 31,320-square-foot, two-story medical office building sits on 1.2 acres and is being offered at $3,800,000-well below the 2026 Bexar Appraisal District value of $4,673,210, creating an outstanding opportunity for investors seeking immediate equity. Currently operating as a medical office building, the property offers flexible suite sizes ranging from 395 SF to 3,957 SF, making it ideal for physicians, specialists, therapists, imaging, wellness providers, and other healthcare professionals. Available space is offered at $24.00 PSF annually ($2.00 PSF monthly), providing an leasing opportunity in a market with continued demand for medical office space. Generating a 8.31 cap rate, this Class C asset combines income with future upside through lease-up and rent optimization. Property Highlights * Sale Price: $3,800,000 * Appraised Value: $4,673,210 (Bexar Appraisal District) * 31,320 SF two-story medical office building * 1.2-acre site * 8.31 Cap Rate * Medical office use with flexible suite configurations * Suites available from 395 SF to 3,957 SF * Lease Rate: $24.00 PSF annually ($2.00 PSF/month) * Excellent opportunity for investors or owner-users Premier Central Location Located just minutes from Downtown San Antonio and the South Texas Medical Center, the property offers outstanding accessibility for patients, physicians, and employees. Its central location provides convenient access to Interstate 10, Loop 410, and major healthcare facilities, making it an ideal destination for medical and professional office users. The surrounding area is one of San Antonio's most established healthcare markets, with a strong concentration of hospitals, specialty clinics, outpatient facilities, and medical professionals. Continued population growth and increasing demand for outpatient healthcare services support long-term demand for quality medical office space in this corridor. Exceptional Visibility & Accessibility The property benefits from exposure to one of San Antonio's busiest transportation corridors. Interstate 10 carries well over 200,000 vehicles per day in this area, while Wurzbach Road experiences approximately 35,000-45,000 vehicles daily, providing exceptional visibility and convenient access for tenants and visitors. Whether you're seeking a stabilized investment with immediate cash flow, a value-add medical office opportunity, or an owner-user property in a high-demand healthcare corridor, this offering delivers outstanding value at a price significantly below appraised value. With strong demographics, exceptional accessibility, and growing demand for medical office space, this is a rare opportunity to acquire a centrally located healthcare asset at a compelling basis.

5902 Computer Dr, San Antonio

Listing courtesy of Listing Agent: Pierre Vasquez (pierre@uriahrealestate.com) from Listing Office: Uriah Real Estate Organization.

Ray Ellison Blvd, San Antonio
$499,000
2002361 MLS
Prime Commercial & Residential Development Opportunity! Exceptional 2.791-acre corner lot located at the highly visible intersection of Ray Ellison Blvd. and Five Palms Dr. This vacant property offers outstanding frontage and accessibility, making it an excellent opportunity for investors, developers, and owner-users alike. The property is currently zoned C-2 (Community Commercial) and RM-4 (Residential Mixed), providing a wide range of potential development options. The C-2 zoning allows for numerous commercial uses including retail, professional offices, restaurants, service businesses, gas stations, entertainment venues, automotive service uses, and more. The RM-4 zoning permits a variety of residential development opportunities including single-family homes, duplexes, triplexes, quadplexes, townhomes, rowhouses, and other low-density multifamily projects. Existing improvements include perimeter fencing, while the remainder of the property is vacant and ready for development. Its strategic location along Ray Ellison Boulevard offers excellent visibility, convenient access, and strong traffic exposure in a rapidly growing area of San Antonio. Whether you're planning a commercial center, mixed-use development, residential project, or investment hold, this property offers exceptional flexibility and long-term potential. Property Details: Location: Corner of Ray Ellison Blvd. & Five Palms Dr. Size: 2.791 Acres Zoning: C-2 (Community Commercial) & RM-4 (Residential Mixed) Legal Description: NCB 15247 BLK LOT P-46 Property ID: 572666 Improvements: Perimeter fencing Current Use: Vacant Land Buyer to independently verify zoning, permitted uses, utilities, development requirements, and all property information with the appropriate governmental authorities.

Ray Ellison Blvd, San Antonio

Listing courtesy of Listing Agent: Manuel Huitron (manuelhn50@gmail.com) from Listing Office: JB Goodwin, REALTORS.

685 S Loop 1604, San Antonio
$900,000
2000007 MLS
Prime Commercial Opportunity on approximately 9.766 acres located on highly traveled Loop 1604 between IH-37 South and IH-35 South. This highly visible corner property is located outside San Antonio city limits (OCL), offering the advantage of no city taxes and greater flexibility for a wide variety of commercial and development opportunities. The existing 1,454 SF commercial building features a spacious open serving area, wet bar, multiple private rooms, office space, restrooms, and ample parking. Originally designed for restaurant and bar use, the flexible floor plan could accommodate numerous business concepts. The property also includes horse stables, an approximately 50-foot-wide by 15-foot-deep man-made pond, and nearly 10 acres of land. An engineer has indicated that approximately 7 acres may be suitable for future RV park or manufactured housing development, subject to buyer verification, engineering, permitting, and governmental approvals. Whether your vision includes a restaurant, bar, event venue, wedding venue, brewery, entertainment destination, RV park, manufactured housing community, equestrian facility, contractor headquarters, storage facility, retail center, or another commercial venture, this property offers the location, visibility, and acreage to bring it to life. Opportunities like this are increasingly rare in one of South Bexar County's fastest-growing corridors. PRIVATE FINANCING AVAILABLE TO THOSE WHO QUALIFY.

685 S Loop 1604, San Antonio

Listing courtesy of Listing Agent: Arianne Villanueva (arianne@thelistingqueen.net) from Listing Office: Teifke Real Estate.

233 Esmeralda Drive, San Antonio
$799,500
1999092 MLS
Discover a rare opportunity to own a modern, furnished 9suite 9.5bth, multifamily residence with a dedicated office, situated on more than half an acre with room to expand. Built just 5.5 years ago, this Mediterraneanstyle property offers exceptional versatility for independent senior living, nonmedical assisted living, student housing, coliving, corporate housing, or specialty group residential use. Each of the 9 private suites features its own full bathroom with tiled walkin shower, spacious closets, trey ceilings in multiple rooms, and all of the on-site furnishings are included. At the center of the building sits a beautiful interior courtyard, visible from all four surrounding corridors, filling the space with natural light and creating a serene, uplifting environment for residents and staff. The common areas offer high ceilings, LED recessed lighting, ceramic tile flooring throughout, and a fully equipped kitchen with stainless steel appliances (2 refrigerators), large island, and abundant cabinetry. A dedicated office space provides an ideal administrative hub for operators. Laundry room with washer and dryer conveys. Exterior highlights include a wide halfmoon driveway with extended pad parking, dual 5ton HVAC systems, a security system, and a spacious backyard with a covered patio. The large lot size provides ample outdoor space and potential for future expansion, additional structures, or enhanced amenities. Located one light from St. Mary's University and minutes from Our Lady of the Lake University, with convenient access to dining, shopping, parks, and public transit. This property offers a unique blend of modern construction, privacy, and operational flexibility-an exceptional opportunity for owneroperators or investors seeking a turnkey, adaptable facility on a generous lot. This property is also available for lease. See MLS 1997274

233 Esmeralda Drive, San Antonio

Listing courtesy of Listing Agent: Sharlette Scott (Sharlette.Scott@gmail.com) from Listing Office: Radiant Realty.

215 Coca Cola Pl Unit 133, San Antonio
$4,336
1998635 MLS
Welcome to The Andy - Where Business Meets Lifestyle in East San Antonio - Discover The Andy, a one-of-a-kind live/work community set in the heart of East San Antonio. Once a bustling Handy Andy distribution center, this reimagined space now serves as a dynamic hub for entrepreneurs, creatives, and small business owners seeking a seamless blend of work and home life. Designed with versatility in mind, The Andy offers a range of thoughtfully curated spaces to fit your business needs: Courtyard-Facing Lofts - Ideal for creative studios, boutique storefronts, or wellness practices, these spaces offer an inviting atmosphere with ample natural light and direct access to the beautifully designed courtyard, perfect for client interactions or a midday recharge. North-Facing Units with Box Truck Landings - Tailor-made for e-commerce brands, small-scale manufacturers, or service-based businesses, these units provide easy load-in/load-out access with dedicated landings for box trucks-minimizing hassle and maximizing efficiency. Private Yard Units - A rare find in urban spaces, these units feature enclosed outdoor areas, perfect for businesses needing additional storage, open-air workspaces, or a private retreat after a long day. Each unit boasts a flexible two-story layout, allowing you to keep business operations on the ground level-whether it's an office, showroom, workshop, or warehouse-while retreating upstairs to a modern, stylish living space. Say goodbye to long commutes, unnecessary overhead, and the inefficiencies of traditional commercial leasing. Located just minutes from IH-35, I-37, I-10, Downtown San Antonio, and the Frost Bank Center, The Andy places you at the center of opportunity. Whether you're launching a new venture, expanding your operations, or simply seeking a smarter, more efficient way to live and work, The Andy is designed to elevate your success. Make your move to where innovation, convenience, and opportunity collide. Welcome to The Andy.

215 Coca Cola Pl Unit 133, San Antonio

Listing courtesy of Listing Agent: Johnny Devora (johnnydevora@devorarealty.com) from Listing Office: Devora Realty.

215 Coca Cola Pl Unit 117, San Antonio
$8,033
1998638 MLS
Welcome to The Andy - Where Business Meets Lifestyle in East San Antonio - Discover The Andy, a one-of-a-kind live/work community set in the heart of East San Antonio. Once a bustling Handy Andy distribution center, this reimagined space now serves as a dynamic hub for entrepreneurs, creatives, and small business owners seeking a seamless blend of work and home life. Designed with versatility in mind, The Andy offers a range of thoughtfully curated spaces to fit your business needs: Courtyard-Facing Lofts - Ideal for creative studios, boutique storefronts, or wellness practices, these spaces offer an inviting atmosphere with ample natural light and direct access to the beautifully designed courtyard, perfect for client interactions or a midday recharge. North-Facing Units with Box Truck Landings - Tailor-made for e-commerce brands, small-scale manufacturers, or service-based businesses, these units provide easy load-in/load-out access with dedicated landings for box trucks-minimizing hassle and maximizing efficiency. Private Yard Units - A rare find in urban spaces, these units feature enclosed outdoor areas, perfect for businesses needing additional storage, open-air workspaces, or a private retreat after a long day. Each unit boasts a flexible two-story layout, allowing you to keep business operations on the ground level-whether it's an office, showroom, workshop, or warehouse-while retreating upstairs to a modern, stylish living space. Say goodbye to long commutes, unnecessary overhead, and the inefficiencies of traditional commercial leasing. Located just minutes from IH-35, I-37, I-10, Downtown San Antonio, and the Frost Bank Center, The Andy places you at the center of opportunity. Whether you're launching a new venture, expanding your operations, or simply seeking a smarter, more efficient way to live and work, The Andy is designed to elevate your success. Make your move to where innovation, convenience, and opportunity collide. Welcome to The Andy.

215 Coca Cola Pl Unit 117, San Antonio

Listing courtesy of Listing Agent: Johnny Devora (johnnydevora@devorarealty.com) from Listing Office: Devora Realty.

298 El Monte Blvd, San Antonio
$530,000
1996122 MLS
Exceptional owner-user or investment opportunity located at the signalized corner of San Pedro Avenue and El Monte Boulevard in the heart of Central San Antonio. Situated on 0.21 acres and zoned C-2, this versatile property features two freestanding buildings totaling approximately 2,255 square feet. The property includes a 1,002 SF former retail/shop building and a 1,253 SF former restaurant building equipped with existing restaurant infrastructure, including a vent hood system. The zoning allows for a wide variety of commercial uses including retail, restaurant, office, service-oriented businesses, medical, professional services, and other neighborhood commercial concepts. Positioned along the heavily traveled San Pedro Avenue corridor, the property benefits from outstanding visibility, convenient access, and strong surrounding demographics. The site is located just north of Downtown San Antonio and minutes from major thoroughfares including US-281, Loop 410, and Interstate 10, providing excellent connectivity throughout the metropolitan area. The surrounding area is anchored by established neighborhoods and major demand drivers including Olmos Park, Monte Vista, The Quarry Market, North Star Mall, San Antonio College, and the thriving San Pedro commercial corridor. Numerous national retailers, restaurants, medical offices, and professional service providers operate nearby, creating strong traffic counts and business synergy. With on-site parking, dual-building functionality, and a highly desirable central location, this property offers an excellent opportunity for owner-occupants, investors, restaurateurs, retailers, or entrepreneurs seeking a well-positioned commercial asset in one of San Antonio's most established business corridors.

298 El Monte Blvd, San Antonio

Listing courtesy of Listing Agent: Uri Uriah (uri@uriahrealestate.com) from Listing Office: Uriah Real Estate Organization.

3079 Martin Luther King Dr, San Antonio
$775,000
1996099 MLS
A rare opportunity is coming to the East Side of San Antonio! Corner of Martin Luther King Dr. & Bellinger. Total of 1.7218 Acres (5 Lots) Excellent visibility with endless redevelopment potential. Prime Commercial Development Opportunity 1.7218 Acres | Five (5) Contiguous Lots Corner of Martin Luther King Dr. & Bellinger Property Address: 3079 Martin Luther King Dr., San Antonio, TX 78220 (Bexar County) Position your next development along one of San Antonio's major east-side corridors. This rare offering includes five contiguous commercial lots totaling approximately 1.7218 acres (75,000 SF) with approximately 200 feet of frontage on Martin Luther King Drive. Located just minutes from Downtown San Antonio, this highly visible corner property offers outstanding redevelopment potential for investors, developers, and owner-users seeking a strategic location with strong traffic exposure and convenient access to major highways. Property Highlights * 1.7218 Acres (75,000 SF) * Approximately 200 feet of frontage on Martin Luther King Drive * Five (5) contiguous lots offered together * Corner location at Martin Luther King Dr. & Bellinger (8,447 traffic counts 2020) * High-visibility commercial corridor and Opportunity Zone * VIA bus stop located on the property corner * Minutes from Downtown San Antonio * Convenient access to IH-10, IH-37 and Loop 410 * Near schools, established neighborhoods and community amenities * Utilities (electrical, water, sewer) available (buyer to independently verify) * Historic Martin Luther King Jr. Day March route Potential Uses * Townhomes & Multifamily Development * Retail Center, Restaurant, Mixed-Use Development * Medical or Professional Office * Automotive Sales or Service (subject to zoning) * Flex Commercial or Religious Facilities * Daycare or Educational Facility (subject to zoning) Buyer to independently verify zoning, utilities, permitted uses, lot dimensions, development requirements and all other information important to the buyer.

3079 Martin Luther King Dr, San Antonio

Listing courtesy of Listing Agent: Melissa Mahula (melissa@homesteadandranch.com) from Listing Office: Homestead & Ranch Real Estate.

5690 Easterling, San Antonio
$850,000
1995204 MLS
Prime commercial opportunity in San Antonio! This 7,500 SF industrial building is situated on a 17,998.99 SF lot and is zoned C-3NA CD, offering excellent flexibility for a variety of commercial and industrial uses (buyer to verify permitted uses). Currently operating as an industrial shop, the property features 14' to 20' ceiling heights throughout the units, providing the vertical clearance needed for warehousing, fabrication, equipment storage, automotive operations, contractors, distribution, and other industrial users. The spacious layout and functional design make it an ideal fit for both owner-users and investors seeking a versatile commercial asset. The nearly 18,000 SF lot provides ample room for parking, equipment storage, and business operations while the property's strategic location offers convenient access to major highways, established commercial corridors, and continued growth throughout the area. Whether you're expanding your business, relocating operations, or adding to your investment portfolio, 5960 Easterling presents a rare opportunity to acquire a well-positioned industrial property in one of San Antonio's growing commercial markets. Property Highlights: 7,500 SF Industrial Building, 17,998.99 SF Lot, C-3NA CD Zoning, 14'-20' Clear Ceiling Heights, Currently operating as an industrial shop, Flexible layout for a variety of commercial uses, Excellent opportunity for owner-users or investors, Listed at $850,000!

5690 Easterling, San Antonio

Listing courtesy of Listing Agent: Ryan Lee (ryanleerealty360@gmail.com) from Listing Office: Texas Ally Real Estate Group.

12502 E Interstate 10, San Antonio
$995,000
1994626 MLS
12502 E IH-10 is a 2.71 acre commercial land opportunity strategically located along Interstate 10 East in the rapidly growing East San Antonio corridor. Featuring direct frontage on IH-10 and excellent visibility, the property offers convenient access to Loop 1604, FM 1518, and major employment centers throughout Northeast Bexar County. The site benefits from its proximity to Randolph Air Force Base, Joint Base San Antonio, Amazon fulfillment facilities, and the rapidly expanding residential communities throughout Converse, Schertz, and East San Antonio. Continued population growth, new housing developments, and expanding infrastructure in the surrounding area make this an attractive opportunity for investors, developers, and owner-users seeking exposure along one of San Antonio's major transportation corridors. The property is currently improved with a 1,064 square foot manufactured home containing three bedrooms and two bathrooms, providing potential interim income or owner-user functionality while planning future development. Utilities including water and electricity are already available on-site, helping reduce development costs and timelines. Zoned C-2 Commercial and R-6 Residential, the property offers flexibility for a variety of commercial, retail, service-oriented, mixed-use, or residential development opportunities. Potential uses include automotive services, contractor yards, equipment sales, retail storefronts, office-warehouse development, self-storage, convenience retail, RV and trailer sales, or redevelopment into a commercial business park. With strong interstate visibility, flexible zoning, existing improvements, utilities on-site, and immediate access to major highways, 12502 E IH-10 presents a rare opportunity to acquire a versatile commercial site in one of the region's fastest-growing submarkets.

12502 E Interstate 10, San Antonio

Listing courtesy of Listing Agent: Uri Uriah (uri@uriahrealestate.com) from Listing Office: Uriah Real Estate Organization.

Start Your Search

IDX information is provided exclusively for consumers' personal, non-commercial use, that it may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing, and that the data is deemed reliable but is not guaranteed accurate by the MLS.  The MLS may, at its discretion, require use of other disclaimers as necessary to protect participants and/or the MLS from liability. 

Listings provided by LERA MLS

How much is your home worth?

Get instant property value now!