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San Antonio Commercial Properties for Sale

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Newest San Antonio Commercial Properties for Sale

$20
2004214 MLS
REAL is pleased to present an exceptional leasing opportunity at 2 Spurs Lane, San Antonio, Texas-a 10,798-square-foot medical office building strategically located in the heart of the San Antonio Medical Center, one of the region's premier healthcare destinations. Constructed in 2012, the property features an attractive stucco and stone exterior with a clay tile roof and offers second-generation medical office space with high-quality interior finishes. The existing medical buildout allows healthcare providers to significantly reduce tenant improvement costs, accelerate occupancy, and begin serving patients with minimal downtime. The building offers flexible leasing configurations designed to accommodate a variety of medical and professional users. The first floor encompasses 5,384 rentable square feet (RSF) and may be leased as a single suite or divided into 1,173 RSF and 4,211 RSF suites. The second floor offers 5,244 RSF as a single contiguous suite. The property also features abundant on-site parking with an excellent 5.09 spaces per 1,000 RSF parking ratio and is available for immediate occupancy. Ideally positioned just one block from Floyd Curl Drive and two blocks from Huebner Road, the property provides outstanding accessibility within the San Antonio Medical Center, one of the largest and most established healthcare hubs in Texas. The surrounding area is anchored by leading healthcare institutions, including University Hospital, Methodist Hospital, and UT Health San Antonio, attracting a large and diverse patient population from across South Texas. This premier location offers medical practices exceptional visibility, convenient patient access, and close proximity to a robust network of physicians, specialists, and healthcare services.

2 Spurs Ln, San Antonio

Listing courtesy of Listing Agent: Gowdhaman Rajan (gowdhamrajan@gmail.com) from Listing Office: Texas Premier Realty.

$849,900
2003866 MLS
Positioned in one of Southeast San Antonio's fastest-growing corridors, this 15.10 acre property offers a rare opportunity to acquire a versatile tract with approximately 540 feet of frontage on Higdon Road, two gated entrances, existing improvements, and outstanding long-term upside. Located outside the San Antonio city limits, the property provides flexibility for a variety of commercial, agricultural, industrial, and residential uses (buyer to verify intended use). The property is improved with a 2,172 square foot residence that can serve as a primary residence, office headquarters, rental property, or employee housing. Additional improvements include a 1,200 square foot workshop, a 240 square foot storage building, and a 320 square foot storage building, making the property immediately functional for an owner-user or business operation. Infrastructure includes two electric meters, a private septic system, and a shallow water well for irrigation, livestock, or agricultural use. A 12-inch SAWS PVC water line runs along Higdon Road (buyer to independently verify availability, capacity, and connection requirements). SAWS Sewer is nearby. The property is fully fenced and benefits from two separate entrances off Higdon Road, allowing for improved traffic circulation and operational flexibility for equipment, trailers, commercial vehicles, or future site improvements. Strategically located just minutes from Loop 410, IH-37, Highway 181, Brooks City Base, Toyota Motor Manufacturing Texas, and the rapidly expanding southeast San Antonio market, the property is surrounded by continued residential and commercial growth, including Lennar's Higdon Crossing, Southton Meadows, Mission del Lago, Monte Viejo, and Highland Hills. Whether you're looking to establish a contractor yard, landscape company, equipment sales operation, agricultural business, storage facility, owner-occupied headquarters, or simply invest in one of San Antonio's expanding growth corridors, this property offers exceptional flexibility and long-term potential.

5084 Higdon, San Antonio

Listing courtesy of Listing Agent: Kari Menchaca (kari@galmrealestate.net) from Listing Office: Galm Real Estate, LLC.

$6,995,000
2003802 MLS
Positioned in the heart of San Antonio's rapidly expanding Westover Hills corridor, this exceptional 38.691 acre tract represents one of the largest remaining undeveloped commercial opportunities in the area. Surrounded by major corporate investment and some of the region's most significant technology infrastructure, the property offers an outstanding opportunity for developers, investors, or end users seeking a highly strategic location with exceptional long-term upside. Bordering three Microsoft data centers and located just minutes from additional facilities operated by companies including CyrusOne, Vantage, Valero, Lowe's, and Frost Bank, the property sits within one of San Antonio's premier employment and technology hubs. The location also provides outstanding access to many of San Antonio's largest destinations, including Christus Santa Rosa Hospital, Northwest Vista College, SeaWorld, Hyatt Regency Hill Country Resort & Spa, and numerous corporate campuses. With quick access to Highway 151, Loop 1604, Culebra Road, Wiseman Boulevard, and Rogers Road, the property offers exceptional connectivity throughout the San Antonio metropolitan area while remaining less than 30 minutes from Downtown. The land features gently rolling topography with approximately 99 percent usable acreage, providing tremendous flexibility for future commercial or industrial development. Approximately half of the property is currently zoned C-2, while the remaining acreage is zoned R-6, with the ability to be rezoned to accommodate commercial uses. The property is not available for residential or multifamily development, making it ideally suited for commercial, industrial, corporate campus, or data center-related projects. Dual access from Impala Summit and Culebra Road further enhances development potential by providing multiple points of ingress and egress. Utilities are readily available, with electricity provided by CPS Energy and water and sewer available at the adjoining subdivision, helping streamline future development.

00 Impala Summit, San Antonio

Listing courtesy of Listing Agent: Joshua Smith (josh@texasland.com) from Listing Office: Keller Williams Realty.

$3,800,000
2003453 MLS
Medical Office Investment Opportunity | Priced Below Appraised Value for Immediate Sale Position your portfolio with this exceptional value-add medical office investment in one of San Antonio's most established healthcare and business corridors. Strategically located near the intersection of Interstate 10 and Wurzbach Road, this 31,320-square-foot, two-story medical office building sits on 1.2 acres and is being offered at $3,800,000-well below the 2026 Bexar Appraisal District value of $4,673,210, creating an outstanding opportunity for investors seeking immediate equity. Currently operating as a medical office building, the property offers flexible suite sizes ranging from 395 SF to 3,957 SF, making it ideal for physicians, specialists, therapists, imaging, wellness providers, and other healthcare professionals. Available space is offered at $24.00 PSF annually ($2.00 PSF monthly), providing an leasing opportunity in a market with continued demand for medical office space. Generating a 8.31 cap rate, this Class C asset combines income with future upside through lease-up and rent optimization. Property Highlights * Sale Price: $3,800,000 * Appraised Value: $4,673,210 (Bexar Appraisal District) * 31,320 SF two-story medical office building * 1.2-acre site * 8.31 Cap Rate * Medical office use with flexible suite configurations * Suites available from 395 SF to 3,957 SF * Lease Rate: $24.00 PSF annually ($2.00 PSF/month) * Excellent opportunity for investors or owner-users Premier Central Location Located just minutes from Downtown San Antonio and the South Texas Medical Center, the property offers outstanding accessibility for patients, physicians, and employees. Its central location provides convenient access to Interstate 10, Loop 410, and major healthcare facilities, making it an ideal destination for medical and professional office users. The surrounding area is one of San Antonio's most established healthcare markets, with a strong concentration of hospitals, specialty clinics, outpatient facilities, and medical professionals. Continued population growth and increasing demand for outpatient healthcare services support long-term demand for quality medical office space in this corridor. Exceptional Visibility & Accessibility The property benefits from exposure to one of San Antonio's busiest transportation corridors. Interstate 10 carries well over 200,000 vehicles per day in this area, while Wurzbach Road experiences approximately 35,000-45,000 vehicles daily, providing exceptional visibility and convenient access for tenants and visitors. Whether you're seeking a stabilized investment with immediate cash flow, a value-add medical office opportunity, or an owner-user property in a high-demand healthcare corridor, this offering delivers outstanding value at a price significantly below appraised value. With strong demographics, exceptional accessibility, and growing demand for medical office space, this is a rare opportunity to acquire a centrally located healthcare asset at a compelling basis.

5902 Computer Dr, San Antonio

Listing courtesy of Listing Agent: Pierre Vasquez (pierre@uriahrealestate.com) from Listing Office: Uriah Real Estate Organization.

$420,000
2000362 MLS
Exceptional opportunity to acquire a freestanding commercial property in one of Northeast San Antonio's growing development corridors. Formerly operated as a neighborhood restaurant, this property features an existing commercial kitchen and restaurant infrastructure, offering a buyer the opportunity to substantially reduce startup costs compared to building a restaurant from the ground up, subject to buyer verification of all permits, inspections, and governmental approvals. The property includes two adjoining commercial units that may be utilized independently or combined into one larger operation, providing flexibility for a restaurant, cafe, bakery, catering business, specialty market, professional office, or other neighborhood-serving commercial use. Ideally located just minutes from Interstate 35, Loop 410, and Loop 1604, the property benefits from excellent accessibility and is surrounded by established neighborhoods, continued residential growth, and ongoing commercial development. The area's expanding population and limited neighborhood dining options create an attractive opportunity for a well-positioned restaurant or other community-serving business. Whether your vision includes reopening a restaurant or establishing another commercial enterprise, this property offers flexibility, visibility, and long-term potential in one of Northeast San Antonio's evolving commercial corridors. Buyers should independently verify zoning, permitted uses, occupancy requirements, permits, and all development requirements.

7030 Branching Ct, San Antonio

Listing courtesy of Listing Agent: Israel Ledesma (israel.ledesma@l4-realty.com) from Listing Office: L4 Realty, LLC.

$319,000
2000301 MLS
Exceptional opportunity to acquire 4.756 acres with both residential and commercial zoning on a frontage road in one of the fastest-growing corridors just minutes from San Antonio. With outstanding development potential, excellent visibility, and flexible zoning, this property is well-suited for a variety of commercial, mixed-use, or investment opportunities, subject to applicable zoning and permitting requirements. The value of the two existing homes are not being considered in the pricing and are being sold AS IS, with the primary value in the land. The level, wooded acreage features mature native trees and offers the flexibility to clear for development or incorporate the natural landscape into your project. Strategically located with convenient access to Loop 1604 and Highway 281, the property's frontage road location provides excellent accessibility and exposure, along with strong connectivity to major employment centers, established residential communities, and a growing customer base. Conveniently located near San Antonio's growing South Side employment corridor, offering easy access to major employers including Toyota Motor Manufacturing, HOLT CAT, TJ Maxx Distribution Center, pharmaceutical manufacturers, healthcare facilities, and numerous logistics and industrial employers-making this an ideal location for commuters.

25365 Us Highway 281 S, San Antonio

Listing courtesy of Listing Agent: Celia Taylor (celia@taylorandtaylorservices.com) from Listing Office: Option One Real Estate.

$900,000
2000007 MLS
Prime Commercial Opportunity on approximately 9.766 acres located on highly traveled Loop 1604 between IH-37 South and IH-35 South. This highly visible corner property is located outside San Antonio city limits (OCL), offering the advantage of no city taxes and greater flexibility for a wide variety of commercial and development opportunities. The existing 1,454 SF commercial building features a spacious open serving area, wet bar, multiple private rooms, office space, restrooms, and ample parking. Originally designed for restaurant and bar use, the flexible floor plan could accommodate numerous business concepts. The property also includes horse stables, an approximately 50-foot-wide by 15-foot-deep man-made pond, and nearly 10 acres of land. An engineer has indicated that approximately 7 acres may be suitable for future RV park or manufactured housing development, subject to buyer verification, engineering, permitting, and governmental approvals. Whether your vision includes a restaurant, bar, event venue, wedding venue, brewery, entertainment destination, RV park, manufactured housing community, equestrian facility, contractor headquarters, storage facility, retail center, or another commercial venture, this property offers the location, visibility, and acreage to bring it to life. Opportunities like this are increasingly rare in one of South Bexar County's fastest-growing corridors. PRIVATE FINANCING AVAILABLE TO THOSE WHO QUALIFY.

685 S Loop 1604, San Antonio

Listing courtesy of Listing Agent: Arianne Villanueva (arianne@thelistingqueen.net) from Listing Office: Teifke Real Estate.

$799,500
1999092 MLS
Discover a rare opportunity to own a modern, furnished 9suite 9.5bth, multifamily residence with a dedicated office, situated on more than half an acre with room to expand. Built just 5.5 years ago, this Mediterraneanstyle property offers exceptional versatility for independent senior living, nonmedical assisted living, student housing, coliving, corporate housing, or specialty group residential use. Each of the 9 private suites features its own full bathroom with tiled walkin shower, spacious closets, trey ceilings in multiple rooms, and all of the on-site furnishings are included. At the center of the building sits a beautiful interior courtyard, visible from all four surrounding corridors, filling the space with natural light and creating a serene, uplifting environment for residents and staff. The common areas offer high ceilings, LED recessed lighting, ceramic tile flooring throughout, and a fully equipped kitchen with stainless steel appliances (2 refrigerators), large island, and abundant cabinetry. A dedicated office space provides an ideal administrative hub for operators. Laundry room with washer and dryer conveys. Exterior highlights include a wide halfmoon driveway with extended pad parking, dual 5ton HVAC systems, a security system, and a spacious backyard with a covered patio. The large lot size provides ample outdoor space and potential for future expansion, additional structures, or enhanced amenities. Located one light from St. Mary's University and minutes from Our Lady of the Lake University, with convenient access to dining, shopping, parks, and public transit. This property offers a unique blend of modern construction, privacy, and operational flexibility-an exceptional opportunity for owneroperators or investors seeking a turnkey, adaptable facility on a generous lot. This property is also available for lease. See MLS 1997274

233 Esmeralda Drive, San Antonio

Listing courtesy of Listing Agent: Sharlette Scott (Sharlette.Scott@gmail.com) from Listing Office: Radiant Realty.

$5,895
1998636 MLS
Welcome to The Andy - Where Business Meets Lifestyle in East San Antonio - Discover The Andy, a one-of-a-kind live/work community set in the heart of East San Antonio. Once a bustling Handy Andy distribution center, this reimagined space now serves as a dynamic hub for entrepreneurs, creatives, and small business owners seeking a seamless blend of work and home life. Designed with versatility in mind, The Andy offers a range of thoughtfully curated spaces to fit your business needs: Courtyard-Facing Lofts - Ideal for creative studios, boutique storefronts, or wellness practices, these spaces offer an inviting atmosphere with ample natural light and direct access to the beautifully designed courtyard, perfect for client interactions or a midday recharge. North-Facing Units with Box Truck Landings - Tailor-made for e-commerce brands, small-scale manufacturers, or service-based businesses, these units provide easy load-in/load-out access with dedicated landings for box trucks-minimizing hassle and maximizing efficiency. Private Yard Units - A rare find in urban spaces, these units feature enclosed outdoor areas, perfect for businesses needing additional storage, open-air workspaces, or a private retreat after a long day. Each unit boasts a flexible two-story layout, allowing you to keep business operations on the ground level-whether it's an office, showroom, workshop, or warehouse-while retreating upstairs to a modern, stylish living space. Say goodbye to long commutes, unnecessary overhead, and the inefficiencies of traditional commercial leasing. Located just minutes from IH-35, I-37, I-10, Downtown San Antonio, and the Frost Bank Center, The Andy places you at the center of opportunity. Whether you're launching a new venture, expanding your operations, or simply seeking a smarter, more efficient way to live and work, The Andy is designed to elevate your success. Make your move to where innovation, convenience, and opportunity collide. Welcome to The Andy.

215 Coca Cola Pl Unit 115, San Antonio

Listing courtesy of Listing Agent: Johnny Devora (johnnydevora@devorarealty.com) from Listing Office: Devora Realty.

$4,336
1998635 MLS
Welcome to The Andy - Where Business Meets Lifestyle in East San Antonio - Discover The Andy, a one-of-a-kind live/work community set in the heart of East San Antonio. Once a bustling Handy Andy distribution center, this reimagined space now serves as a dynamic hub for entrepreneurs, creatives, and small business owners seeking a seamless blend of work and home life. Designed with versatility in mind, The Andy offers a range of thoughtfully curated spaces to fit your business needs: Courtyard-Facing Lofts - Ideal for creative studios, boutique storefronts, or wellness practices, these spaces offer an inviting atmosphere with ample natural light and direct access to the beautifully designed courtyard, perfect for client interactions or a midday recharge. North-Facing Units with Box Truck Landings - Tailor-made for e-commerce brands, small-scale manufacturers, or service-based businesses, these units provide easy load-in/load-out access with dedicated landings for box trucks-minimizing hassle and maximizing efficiency. Private Yard Units - A rare find in urban spaces, these units feature enclosed outdoor areas, perfect for businesses needing additional storage, open-air workspaces, or a private retreat after a long day. Each unit boasts a flexible two-story layout, allowing you to keep business operations on the ground level-whether it's an office, showroom, workshop, or warehouse-while retreating upstairs to a modern, stylish living space. Say goodbye to long commutes, unnecessary overhead, and the inefficiencies of traditional commercial leasing. Located just minutes from IH-35, I-37, I-10, Downtown San Antonio, and the Frost Bank Center, The Andy places you at the center of opportunity. Whether you're launching a new venture, expanding your operations, or simply seeking a smarter, more efficient way to live and work, The Andy is designed to elevate your success. Make your move to where innovation, convenience, and opportunity collide. Welcome to The Andy.

215 Coca Cola Pl Unit 133, San Antonio

Listing courtesy of Listing Agent: Johnny Devora (johnnydevora@devorarealty.com) from Listing Office: Devora Realty.

$8,033
1998638 MLS
Welcome to The Andy - Where Business Meets Lifestyle in East San Antonio - Discover The Andy, a one-of-a-kind live/work community set in the heart of East San Antonio. Once a bustling Handy Andy distribution center, this reimagined space now serves as a dynamic hub for entrepreneurs, creatives, and small business owners seeking a seamless blend of work and home life. Designed with versatility in mind, The Andy offers a range of thoughtfully curated spaces to fit your business needs: Courtyard-Facing Lofts - Ideal for creative studios, boutique storefronts, or wellness practices, these spaces offer an inviting atmosphere with ample natural light and direct access to the beautifully designed courtyard, perfect for client interactions or a midday recharge. North-Facing Units with Box Truck Landings - Tailor-made for e-commerce brands, small-scale manufacturers, or service-based businesses, these units provide easy load-in/load-out access with dedicated landings for box trucks-minimizing hassle and maximizing efficiency. Private Yard Units - A rare find in urban spaces, these units feature enclosed outdoor areas, perfect for businesses needing additional storage, open-air workspaces, or a private retreat after a long day. Each unit boasts a flexible two-story layout, allowing you to keep business operations on the ground level-whether it's an office, showroom, workshop, or warehouse-while retreating upstairs to a modern, stylish living space. Say goodbye to long commutes, unnecessary overhead, and the inefficiencies of traditional commercial leasing. Located just minutes from IH-35, I-37, I-10, Downtown San Antonio, and the Frost Bank Center, The Andy places you at the center of opportunity. Whether you're launching a new venture, expanding your operations, or simply seeking a smarter, more efficient way to live and work, The Andy is designed to elevate your success. Make your move to where innovation, convenience, and opportunity collide. Welcome to The Andy.

215 Coca Cola Pl Unit 117, San Antonio

Listing courtesy of Listing Agent: Johnny Devora (johnnydevora@devorarealty.com) from Listing Office: Devora Realty.

$1,499,990
1998220 MLS
For Sale - Lease Considered for the Right Tenant! Exceptional opportunity to acquire approximately 1.74 acres of commercially zoned land in the highly desirable Northwest San Antonio corridor near UTSA, IH-10, and Loop 1604. The property features an existing 2,095 SF building, formerly used as a residence and later converted to office space, offering flexibility for an owner-user, investor, or redevelopment project. The building requires repairs and remodeling and is being sold as-is. The site also needs clearing and cleanup to maximize its full potential. The true value of this property lies in the land and its outstanding redevelopment opportunity. With approximately 75,794 SF (1.74 acres), the site is well suited for a variety of commercial uses, including professional offices, contractor yard, landscaping business, fleet or truck parking (subject to applicable regulations), storage, medical office, educational facility, event center, or future mixed-use or multifamily redevelopment, subject to zoning and municipal approvals. The existing structure may also be adapted for a business with on-site living quarters, making it an attractive option for owner-operators. Conveniently located just minutes from UTSA, The Shops at La Cantera, The Rim, the South Texas Medical Center, and major employers, this property offers excellent accessibility and long-term investment potential. Also available for lease to a qualified tenant under acceptable terms. Rare opportunity to secure a large commercial tract in one of San Antonio's fastest-growing business corridors. Buyer to verify all zoning, permitted uses, measurements, and development requirements.

5321 Casa Bella, San Antonio

Listing courtesy of Listing Agent: Ameen Aziz (azizintx@gmail.com) from Listing Office: Citywide Realty, LLC.

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